The Clinical and Pharmacological Actions of the TCM formula “Yi Gan San” (Restrain the Liver Powder)
Introduction
The traditional Chinese herbal formula Yi Gan San (YGS) was recorded by Xue Kai (a.k.a. Xue Liang-wu) in the Bao Ying Cuo Yao (Synopsis of Caring for Infants), 1555. It was originally intended for pediatric use in cases with spasms, feverishness, bruxism, anxiety with palpitations, and restless sleep with terrifying nightmares. In contemporary practice its clinical applications have been expanded to include temper tantrums, irritability, impatience aggressiveness and insomnia. (1) In Japan, it is approved for clinical use by the …